The present study was aimed to evaluate the growth inhibitory effect of Hibiscus rosasinensis, Azadirachta indica, Ficus religiosa and Ocimum sanctum leaves extracts on Esherichia coli, Salmonella typhii, Staphylococcus aureus and Enterobacter aerogen. Aquous plant extracts were tested against 4 bacteria. Gel diffusion method, were used in this investigation. The antibacterial activity of Azadirachta indica plant extract was exhibited maximum zone of inhibition against Esherichia coli 15 mm (Mean value in Dia.), when compared with other medicinal plant extracts. Ficus religiosa plant extract was zone of inhibition 14 mm (Mean value in Dia.) against Esherichia coli and 12 mm (Mean value in Dia.) against Salmonella typhii, Staphylococcus aureus and Enterobacter aerogen. The Enterobacter aerogen was highly inhibition 9 mm (Mean value in Dia.) against Ocimum sanctum plant extract. At the same time Hibiscus rosasinensis plant extract was highly sensitive 14 mm (Mean value in Dia.) against Staphylococcus aureus. The present observation, the Azadirachta indica and Ficus religiosa medicinal plant extracts are having best control of antibacterial activity.
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